Bioavailability Enhancer

BioPerine® (Black Pepper Extract)

BioPerine® (standardized to 95% piperine) inhibits intestinal alkaline phosphatase and P-glycoprotein — two enzymes that break down and expel many supplements before they can be absorbed.

How It Works

BioPerine® (standardized to 95% piperine) inhibits intestinal alkaline phosphatase and P-glycoprotein — two enzymes that break down and expel many supplements before they can be absorbed. It also stimulates amino acid transporters in the intestinal wall, increasing the absorption rate of co-administered nutrients. The net effect is dramatically improved bioavailability of fat-soluble and water-soluble compounds.

Why It's in Our Formulas

Included to maximize the effectiveness of every other ingredient in the formula. Without BioPerine®, many of the fat-soluble compounds (curcumin, CoQ10, fat-soluble vitamins) would be poorly absorbed. At 5mg, BioPerine® can increase the bioavailability of co-administered nutrients by 20–2000% depending on the compound.

Clinical Evidence

BioPerine® is one of the most studied bioavailability enhancers. A landmark study showed 2000% increase in curcumin bioavailability when combined with piperine. Multiple studies confirm enhanced absorption of CoQ10, selenium, vitamin B6, and beta-carotene.

Dosing & Timing

5–10mg per serving is the effective dose. Always take the entire formula together to benefit from BioPerine's absorption enhancement. No additional dosing required.

* These statements have not been evaluated by the Food and Drug Administration. This content is for educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease.