Nootropic

Alpha-GPC (Alpha-Glycerylphosphorylcholine)

Alpha-GPC is the most bioavailable form of choline — it crosses the blood-brain barrier efficiently and directly increases acetylcholine synthesis in the hippocampus and prefrontal cortex.

How It Works

Alpha-GPC is the most bioavailable form of choline — it crosses the blood-brain barrier efficiently and directly increases acetylcholine synthesis in the hippocampus and prefrontal cortex. Acetylcholine is the primary neurotransmitter for memory encoding, attention, and neuroplasticity. Alpha-GPC also supports the release of growth hormone and has neuroprotective properties.

Why It's in Our Formulas

Provides the direct choline precursor needed for acetylcholine synthesis — the rate-limiting step in memory and focus. While Huperzine-A preserves existing acetylcholine, Alpha-GPC increases its production. Together, they create a complete acetylcholine optimization stack.

Clinical Evidence

Multiple clinical trials in cognitive decline and healthy adults. A 2003 study showed significant improvement in cognitive function in Alzheimer's patients. Studies in healthy adults confirm improved attention, memory, and power output. Alpha-GPC is used in European countries as a prescription medication for cognitive decline.

Dosing & Timing

300–600mg daily. Best taken in the morning with food. May cause vivid dreams in some individuals when taken at night. Synergistic with Huperzine-A and Bacopa for comprehensive cognitive support.

* These statements have not been evaluated by the Food and Drug Administration. This content is for educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease.